Español (spanish formal Internacional)English (United Kingdom)French (Fr)

Anti-epileptic drugs

E-mail Print PDF
 

FARMACOS Epilepsy can constrain a person's personal life, school life, academia, work life and family and social life, and will negatively impact on the individual.

An epileptic diagnosis must be correct and undeniable. The more delay there is in starting anti-epileptic treatment the more difficult it will be to control seizures.

In half of all patients seizures are controlled with the first drug that is tried and for another 20% with the second drug tried (always in monotherapy). It is very important to choose from the start the most efficient and best tolerated anti-epileptic drug.

 

Factors to take into account when selecting the ideal drug. 

  • Type of epilepsy: it is important to identify which type of epilepsy the patient has so as to choose the most appropriate anti-epileptic drug.
  • Type of epileptic seizure: need to clinically diferentiate through the use of an EEG or video EEG the seizure type.
  • Seizure frequency: when seizure frequency is high it may be recommended that a drug which can be introduced rapidly is used, in some cases via parenteral.
  • Type of EEG differences.
  • Type of drug: the drug that will be used should have the best characteristics both in pharmacokinetics and pharmacodynamic possible.
  • Taking drugs: drug dosage is calculated according to the age and weight of the patient. The number of daily dosages will be determined by how quickly the drugs are eliminated from the system.
  • Treatment compliance: drugs that only require 1 or 2 doses a day should be selected, especially in adolescents or in people where there is a higher risk of errors or forgetting to take the drugs regularly.
 
Generic

nuevos farmacosThe drug budget in Spain increases between 5% and 12% annually, and there is a need to put into place measures to reduce the budget.

The principal attribute of generic drugs is their low cost which represents a saving for health providers. But EFG's (specialty generic pharmaceuticals) also have disadvantages: the speed and degree of absorption can change when the physical-chemical charcateristics (size of the particles, excipients, etc.) are different from named drugs, determining differences in plasma concentrations can be responsable for negative efects in treatment efficiency and tolerance.

Read more...
Pediatric classics

clasicos en pediatraCarbamazepine (Tegretol®).
Is an FAE (Fármaco AntiEpiléptico/anti-epileptic drug) efficient for partial seizures and sometimes for generalised tonic-clonic seizures. Taken in two daily dosis, the therapuetic range is 4-8mg/L.

Read more...
New drugs

farmacos antiepilepticosGabapentin (Neurontin®)
It is a drug that has been used widely to treat partial seizures. Currently it is used for other pathologies especially, neuropathic pain, migrane, bipolar disorder, trembling and others.

Rufinamide (Inovelon®)
The last drug to appear on the market this year . It is specifically used for Lennox-Gastaut Syndrome.

Read more...
Side effects

efectos adversosSide effects are all those effects not desired or sought when administering a drug. 

Some side effects can be positive when they improve the symtoms of other illnesses that the patient might have (for example topiramate can improve migrane), others are negative because they are unpleasant or annoying indeed some can put the patient's health at risk. When you notice something that you think might be related to the drugs you are taking get in touch with your GP or even better your neurologist. If the discomfort is important go to accident and emergency straight away.

Read more...

Upcoming events

Ver calendario completo

Vídeos relacionados

Powered by mod LCA

Donations

Thank you for collaborating with us.